Metabolic Avatar
AI-Driven Precision Nutrition & Metabolic Modeling​
In a world where precision nutrition and personalized health are transforming how we prevent disease and optimize performance, traditional models of metabolism are no longer enough. The Metabolic Avatar represents a new frontier: an AI-driven system designed to model and predict your body’s unique metabolic responses in real time. What began as a Personalized Metabolic Avatar (PMA)—tailored to individual physiology, diet, and lifestyle—has evolved into a scalable Generalized Metabolic Avatar (GMA), capable of supporting entire populations with adaptive nutrition plans. Powered by data from wearable devices, dietary tracking, and cutting-edge machine learning algorithms, the Metabolic Avatar goes beyond calories. It integrates insights from gut microbiota, hormonal cycles, immune response, and even quantum-level biological dynamics to deliver a truly holistic view of human metabolism. This journey—from manual self-monitoring to intelligent metabolic forecasting—marks a paradigm shift in how we understand and manage health. Whether you are an athlete, a clinician, or someone seeking better well-being, the Metabolic Avatar is your gateway to a future of hyper-personalized, real-time metabolic optimization.
Research Timeline:
The Evolution of the Metabolic Avatar
Next Step: Expanding QMA into the Generalized Quantum Metabolic Avatar (Q-GMA), combining quantum AI with large-scale metabolic predictions
References
[1] Bianchetti, G.; Abeltino, A.; Serantoni, C.; Ardito, F.; Malta, D.; De Spirito, M.; Maulucci, G. Personalized Self-Monitoring of Energy Balance through Integration in a Web-Application of Dietary, Anthropometric, and Physical Activity Data. J. Pers. Med. 2022, 12, 568. https://doi.org/10.3390/jpm12040568
[2] Abeltino, A.; Bianchetti, G.; Serantoni, C.; Ardito, C.F.; Malta, D.; De Spirito, M.; Maulucci, G. Personalized Metabolic Avatar: A Data Driven Model of Metabolism for Weight Variation Forecasting and Diet Plan Evaluation. Nutrients 2022, 14, 3520. https://doi.org/10.3390/nu14173520
[3] Abeltino, A.; Bianchetti, G.; Serantoni, C.; Riente, A.; De Spirito, M.; Maulucci, G. Putting the Personalized Metabolic Avatar into Production: A Comparison between Deep-Learning and Statistical Models for Weight Prediction. Nutrients 2023, 15, 1199. https://doi.org/10.3390/nu15051199
[4] Abeltino, A.; Bianchetti, G.; Serantoni, C.; Riente, A.; De Spirito, M.; Maulucci, G. Digital Biohacking Approach to Dietary Interventions: A Comprehensive Strategy for Healthy and Sustainable Weight Loss. Nutrients 2024, 16, 2021. https://doi.org/10.3390/nu16132021
[5] Bianchetti, G.; De Maio, F.; Abeltino, A.; Serantoni, C.; Riente, A.; Santarelli, G.; Sanguinetti, M.; Delogu, G.; Martinoli, R.; Barbaresi, S.; et al. Unraveling the Gut Microbiome–Diet Connection: Exploring the Impact of Digital Precision and Personalized Nutrition on Microbiota Composition and Host Physiology. Nutrients 2023, 15, 3931. https://doi.org/10.3390/nu15183931
[6] A. Abeltino, C. Serantoni, A. Riente, M. De Giulio, S. Capezzone, R. Esposito, M. De Spirito, G. Maulucci. Transforming personalized weight forecasting: From the Personalized Metabolic Avatar to the Generalized Metabolic Avatar, Computers in Biology and Medicine, 2025. https://doi.org/10.1016/j.compbiomed.2025.109879.
[7] M. De Giulio, A. Abeltino, C. Serantoni, A. Riente, S. Capezzone, R. Esposito, M. De Spirito, G. Maulucci. Quantum Metabolic Avatar: a Digital Replica of Metabolism Enhanced by Quantum Algorithms - Under Review